naltrexone

What medications can help patients with alcohol use disorder reduce their drinking, other than naltrexone?

While the only FDA approved medications for AUD are naltrexone (best evidence!), acamprosate, and disulfiram, non-FDA approved topiramate and gabapentin can also help reduce heavy drinking with emerging evidence for GLP-1 agonists.

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What treatments help patients stop using methamphetamine?

Contingency management (incentivizing and rewarding positive behavior change) is the standard of care, most evidence-based treatment for pts w/ stimulant use disorder (StUD). While there are no FDA-approved medications for StUD, mirtazapine and naltrexone+bupropion Xl show promise for reduction in stim use.

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